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AI cracks superbug problem in two days that took scientists years

tidesofentropy.co.uk Published: 21 February 2025 | Updated: 21 February 2025 4 minutes read
34 views
Bugs

21/02/2025 It is extremely rare for me to use third party content on my website but, due to the profound, (though simple), telling of this story that I’ve copy and pasted directly from BBC online news, we get an opportunity to digest and fully comprehend just what the potential for AI is likely to involve in the coming months and years.

Cases of tuberculosis have increased in the UK and worldwide as the disease increases its resistance to antibiotics

Tom Gerken

Technology reporter

A complex problem that took microbiologists a decade to get to the bottom of has been solved in just two days by a new artificial intelligence (AI) tool.

Professor José R Penadés and his team at Imperial College London had spent years working out and proving why some superbugs are immune to antibiotics.

He gave “co-scientist” – a tool made by Google – a short prompt asking it about the core problem he had been investigating and it reached the same conclusion in 48 hours.

He told the BBC of his shock when he found what it had done, given his research was not published so could not have been found by the AI system in the public domain.

“I was shopping with somebody, I said, ‘please leave me alone for an hour, I need to digest this thing,'” he told the Today programme, on BBC Radio Four.

“I wrote an email to Google to say, ‘you have access to my computer, is that right?'”, he added.

The tech giant confirmed it had not.

The full decade spent by the scientists also includes the time it took to prove the research, which itself was multiple years.

But they say, had they had the hypothesis at the start of the project, it would have saved years of work.

Prof Penadés’ said the tool had in fact done more than successfully replicating his research.

“It’s not just that the top hypothesis they provide was the right one,” he said.

“It’s that they provide another four, and all of them made sense.

“And for one of them, we never thought about it, and we’re now working on that.”

Bugged by superbugs

The researchers have been trying to find out how some superbugs – dangerous germs that are resistant to antibiotics – get created.

Their hypothesis is that the superbugs can form a tail from different viruses which allows them to spread between species.

Prof Penadés likened it to the superbugs having “keys” which enabled them to move from home to home, or host species to host species.

Critically, this hypothesis was unique to the research team and had not been published anywhere else. Nobody in the team had shared their findings.

So Mr Penadés was happy to use this to test Google’s new AI tool.

Just two days later, the AI returned a few hypotheses – and its first thought, the top answer provided, suggested superbugs may take tails in exactly the way his research described.

‘This will change science’

The impact of AI is hotly contested.

Its advocates say it will enable scientific advances – while others worry it will eliminate jobs.

Prof Penadés said he understood why fears about the impact on jobs such as his was the “first reaction” people had but added “when you think about it it’s more that you have an extremely powerful tool.”

He said the researchers on the project were convinced that it would prove very useful in the future.

“I feel this will change science, definitely,” Mr Penadés said.

“I’m in front of something that is spectacular, and I’m very happy to be part of that.

“It’s like you have the opportunity to be playing a big match – I feel like I’m finally playing a Champions League match with this thing.”

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About the Author

26 years ago, in my early 40s, I unwittingly imploded my 20 year love story of a marriage by allowing an extra-ordinary run of local, national and international business success in innovation and design entirely derail my private life.

Meaning, in doing what society expects of us, by striving and succeeding in being brave, risk averse and entrepreneurial, I allowed the pursuit of business ambitions to destroy everything I ever held dear.

Unable to process that reality, I turned to a brand new technology: the World Wide Web where I found solace and meaning speaking openly to others.

Initially, as user “On The Beach”, (OTB) that persona acted as a foil and online way for Chris to discuss and face difficult truths his real-world self could not and would not face or acknowledge.

Later though several years before the advent of Facebook, followers, fans or subscribers, under the pseudo name of Beach, I would gain thousands of loyal individual online friends who came to appreciate and look forward to reading my idiosyncratic, often deep and meaningful posts on an array of giant global forums and online watering holes across the world.

I was writing about and debating artificial intelligence and the need to one day develop morals and rights for non living digital life forms as far back as 2002 and also included topics such as “Martian Colony Planning” in the days when Nasa’s JPL lab was Earth’s only hope for putting the first human on the red planet.

Anyway, Beach became the voice I used whenever I was interacting online, a role he has now hosted on my behalf for more than twenty-five years.

As a result, particularly within these pages, Beach Thorncombe’s voice is often louder than Chris’s ever would be.

That said, Beach is not some split personality of mine. Rather he is simply my alter ego, (Like Bowie’s “Ziggy Stardust” or Eric Arthur Blair’s “George Orwell” except, unlike either of those Stardust / Orwell fictional nom de plumes, Beach is the raw authentic, fiercely intellectual side of the Chris you may already know or knew.

Enjoy!

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